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Article

Leading determinants of incident dementia among individuals with and without the apolipoprotein E ε4 genotype: a retrospective cohort study.

BMC neurology - 20 Feb 2024

Ye Siting, Roccati Eddy, Wang Wei, Zhu Zhuoting, Kiburg Katerina, Huang Yu, Zhang Xueli, Zhang Xiayin, Liu Jiahao, Tang Shulin, Hu Yijun, Ge Zongyuan, Yu Honghua, He Mingguang, Shang Xianwen

Abstract excerpt

BACKGROUND: Little is known regarding the leading risk factors for dementia/Alzheimer's disease (AD) in individuals with and without APOE4. The identification of key risk factors for dementia/Alzheimer's disease (AD) in individuals with and without the APOE4 gene is of significant importance in global health. METHODS: Our analysis included 110,354 APOE4 carriers and 220,708 age- and sex-matched controls aged...

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Identifiers

PMID: 38378514
DOI: 10.1186/s12883-024-03557-8
PMCID: PMC10877929

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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