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Article

Association of MICA and NKG2D genetic variants with disease susceptibility and outcome of anti-TNF therapy in patients with axial spondyloarthritis.

Clinical and experimental rheumatology - 1 Jul 2024

Wielińska Joanna, Bugaj Bartosz, Świerkot Jerzy, Kolossa Katarzyna, Iwaszko Milena, Jeka Sławomir, Bogunia-Kubik Katarzyna

Abstract excerpt

OBJECTIVES: The disruption of the NKG2D-MICA axis can induce an enhanced immune response and promote autoimmune processes during axial spondyloarthritis (axSpA) pathogenesis. We aimed to investigate potential relationships between selected single nucleotide polymorphisms within the MICA and NKG2D genes and disease susceptibility and clinical parameters in axSpA patients treated with TNF inhibitors. METHODS:...

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Identifiers

PMID: 38372728
DOI: 10.55563/clinexprheumatol/l5346i

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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