Frequency and Clinicopathological Characteristics of Patients With KRAS/BRAF Double-Mutant Colorectal Cancer: An In Silico Study.

doi:10.3389/pore.2022.1610206

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Article

Frequency and Clinicopathological Characteristics of Patients With KRAS/BRAF Double-Mutant Colorectal Cancer: An In Silico Study.

Pathology oncology research : POR - 1 Jan 2022

Uchida Shiro, Kojima Takaaki, Sugino Takashi

Abstract excerpt

KRAS and BRAF mutations are currently thought to be mutually exclusive as their co-occurrence is extremely rare. Therefore, clinicopathological and molecular characteristics of colorectal carcinoma with KRAS/BRAF double mutations are unclear. We aimed to investigate the frequency and clinicopatho...

Topics

Colorectal Neoplasms
Humans
Male
Microsatellite Instability
Mutation
Proto-Oncogene Proteins B-raf
Proto-Oncogene Proteins p21(ras)

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