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Article

Molecular pathological epidemiology of colorectal cancer in Chinese patients with KRAS and BRAF mutations.

Oncotarget - 24 Nov 2015

Li Wenbin, Qiu Tian, Ling Yun, Guo Lei, Li Lin, Ying Jianming

Abstract excerpt

An investigation of interactive effects of exogenous and endogenous factors and tumor molecular changes can lead to a better understanding of tumor molecular signatures in colorectal cancer. We here report a molecular pathological epidemiology study in a large cohort of 945 colorectal cancer patients. Mutations of KRAS (36.6%) and BRAF (3.46%) were nearly mutually exclusive. KRAS-mutated tumors were more common...

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Identifiers

PMID: 26530529
DOI: 10.18632/oncotarget.5551
PMCID: PMC4741849

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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