Article
Cancer risks among first-degree relatives of women with a genetic predisposition to breast cancer.
Journal of the National Cancer Institute - 7 Jun 2024
Xiao Qingyang, Mao Xinhe, Ploner Alexander, Grassmann Felix, Rodriguez Juan, Eriksson Mikael, Hall Per, Czene Kamila
Abstract excerpt
BACKGROUND: Associations between germline alterations in women and cancer risks among their relatives are largely unknown. METHODS: We identified women from 2 Swedish cohorts Karolinska Mammography Project for Risk Prediction of Breast Cancer (KARMA) and prevalent KARMA (pKARMA), including 28 362 women with genotyping data and 13 226 with sequencing data. Using Swedish Multi-Generation Register, we linked these...
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