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Article

Genetic susceptibility to breast cancer.

Molecular oncology - 1 Jun 2010

Mavaddat Nasim, Antoniou Antonis C, Easton Douglas F, Garcia-Closas Montserrat

Abstract excerpt

Genetic and lifestyle/environmental factors are implicated in the aetiology of breast cancer. This review summarizes the current state of knowledge on rare high penetrance mutations, as well as moderate and low-penetrance genetic variants implicated in breast cancer aetiology. We summarize recent discoveries from large collaborative efforts to combine data from candidate gene studies, and to conduct genome-wide...

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Source

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Identifiers

PMID: 20542480
DOI: 10.1016/j.molonc.2010.04.011
PMCID: PMC5527934

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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