Article

Hereditary Breast Cancer: Comprehensive Risk Assessment and Prevention Strategies

2024-11-29

Abstract excerpt

Women carrying pathogenic/likely pathogenic (P/LP) variants in moderate- or high-penetrance genes have an increased risk of developing breast cancer. However, most P/LP variants associated with breast cancer risk show incomplete penetrance. Age, gender, family history, polygenic risk, lifestyle, reproductive, hormonal, and environmental factors can affect the expressivity and penetrance of the disease. However, th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 357993da-68a2-5282-9b07-b5aa16bb6385
DOI: 10.20944/preprints202411.2323.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hereditary Breast Cancer: Comprehensive Risk Assessment and Prevention StrategiesDOI 10.20944/preprints202411.2323.v1Read

Breast cancer genetics and risk assessment: an overview for the clinician.Semantic proximity Read

Breast cancer genetics: what we know and what we need.Semantic proximity Read

Hereditary breast cancer syndromes and genetic testingSemantic proximity Read

Breast cancer genetics and risk assessment 101: What women's health care providers need to know.Semantic proximity Read

Hereditary breast cancer: an update on risk assessment and genetic testing in 2015.Semantic proximity Read

Genetics of Breast Cancer: Risk Models, Who to Test, and Management Options.Semantic proximity Read

Genetic determinants of breast cancer risk: a review of current literature and issues pertaining to clinical application.Semantic proximity Read

Updates in hereditary breast cancer genetic testing and practical high risk breast management in gene carriers.Semantic proximity Read

Next-generation sequencing for inherited breast cancer risk: counseling through the complexity.Semantic proximity Read

BRCA and beyond: a genome-first approach to familial breast cancer risk assessment.Semantic proximity Read

Breast Cancer Genetics and Indications for Prophylactic Mastectomy.Semantic proximity Read

Assessing, Counseling, and Treating Patients at High Risk for Breast Cancer.Semantic proximity Read