Article
The Association Between Genetic Variants in ACE1and ACE2 Genes with Susceptibility to COVID-19 Infection.
Biochemical genetics - 1 Dec 2024
Abbaszadeh Hamid, Kabiri-Rad Hamid, Mohammadi Fariba, Zangoie Soheila, Rajabi-Moghaddam Mahdieh, Ghafari Shokouh, Ziaee Masood, Javanmard Davod, Miri-Moghaddam Ebrahim
Abstract excerpt
Angiotensin-converting enzyme 2 (ACE2) receptors facilitate the entry of the causative virus severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) into target cells. Some ACE gene variants have been suggested to be involved in COVID-19 pathogenesis. So, the aim was to assess the association between ACE1 rs4646994 and ACE2 rs2285666 genes polymorphisms and the susceptibility and severity of COVID-19. This...
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