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Article

Polymorphism of Angiotensin-Converting Enzyme 2 Gene (rs 2285666) and its susceptibility to COVID-19 infection and severity of the disease.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Mar 2026

Elshewaikh Hend Samir Abdelkader, Attia Gihan Farouk, Ibrahim Wesam Salah Mohamed, Sharshar Ragia Samir, Ali Dina A

Abstract excerpt

Single-nucleotide polymorphisms may alter severe acute respiratory syndrome virus 2 (SARS-CoV-2) binding or entry and increase lung or other organ tissue damage in the most prevalent genes, angiotensin-converting enzyme 2 (ACE2) and its close relative, ACE1. The goal of this study was to look at the severity of the illness, the involvement of the ACE2 gene polymorphism, and its vulnerability to coronavirus...

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Source

Identifiers

PMID: 40459007
DOI: 10.1177/10815589251348921

Genes

ACE2

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