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Article

ACE2 and TMPRSS2 SNPs as Determinants of Susceptibility to, and Severity of, a COVID-19 Infection.

British journal of biomedical science - 1 Jan 2022

Abdelsattar S, Kasemy Z A, Ewida S F, Abo-Elsoud R A A, Zytoon A A, Abdelaal G A, Abdelgawad A S, Khalil F O, Kamel H F M

Abstract excerpt

Background: Genetic risk factors may be related to the infectivity and severity of SARS-CoV-2 infection. Angiotensin-converting enzyme 2 (ACE2) and host transmembrane serine protease (TMPRSS2) have key role in viral cell entrance and priming. Methods: This case-control study on 147 healthy controls and 299 COVID-19 patients identified potential determinants and risk factors, including gene polymorphism involved...

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Identifiers

PMID: 35996506
DOI: 10.3389/bjbs.2021.10238
PMCID: PMC8915702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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