Differential allelic representation (DAR) identifies candidate eQTLs and improves transcriptome analysis.

Abstract excerpt

In comparisons between mutant and wild-type genotypes, transcriptome analysis can reveal the direct impacts of a mutation, together with the homeostatic responses of the biological system. Recent studies have highlighted that, when the effects of homozygosity for recessive mutations are studied in non-isogenic backgrounds, genes located proximal to the mutation on the same chromosome often appear over-represented...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gene Expression Profiling
• Share to Genotype