Segregating variation in the transcriptome: cis regulation and additivity of effects.

Abstract excerpt

Properties of genes underlying variation in complex traits are largely unknown, especially for variation that segregates within populations. Here, we evaluate allelic effects, cis and trans regulation, and dominance patterns of transcripts that are genetically variable in a natural population of Drosophila melanogaster. Our results indicate that genetic variation due to the third chromosome causes mainly additive...

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• Drosophila melanogaster
• Gene Expression Regulation
• Gene Frequency
• Genetic Variation
• Oligonucleotide Array Sequence Analysis