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Article

Defining Nephritic Factors as Diverse Drivers of Systemic Complement Dysregulation in C3 Glomerulopathy

30 Nov 2023

Abstract excerpt

(word count=248 / 250) Introduction C3 Glomerulopathy (C3G) is an ultra-rare renal disease characterized by deposition of complement component C3 in the glomerular basement membrane. Rare and novel genetic variation in complement genes and autoantibodies to complement proteins are commonly identified in the C3G population and thought to drive the underlying complement dysregulation that results in renal damage;...

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PMID: 38344720
DOI: 10.1016/j.ekir.2023.11.025

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