C3 Glomerulopathy and Related Disorders in Children: Etiology-Phenotype Correlation and Outcomes.

doi:10.2215/CJN.00320121

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Article

C3 Glomerulopathy and Related Disorders in Children: Etiology-Phenotype Correlation and Outcomes.

Clinical journal of the American Society of Nephrology : CJASN - 1 Nov 2021

Wong Edwin K S, Marchbank Kevin J, Lomax-Browne Hannah, Pappworth Isabel Y, Denton Harriet, Cooke Katie, Ward Sophie, McLoughlin Amy-Claire, Richardson Grant, Wilson Valerie, Harris Claire L, Morgan B Paul, Hakobyan Svetlana, McAlinden Paul, Gale Daniel P, Maxwell Heather, Christian Martin, Malcomson Roger, Goodship Timothy H J, Marks Stephen D, Pickering Matthew C, Kavanagh David, Cook H Terence, Johnson Sally A

Abstract excerpt

BACKGROUND AND OBJECTIVES: Membranoproliferative GN and C3 glomerulopathy are rare and overlapping disorders associated with dysregulation of the alternative complement pathway. Specific etiologic data for pediatric membranoproliferative GN/C3 glomerulopathy are lacking, and outcome data are based on retrospective studies without etiologic data. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: A total of 80...

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PMID: 34551983
DOI: 10.2215/CJN.00320121
PMCID: PMC8729419

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