Article
A Missense Variant in TP53 Could Be a Genetic Biomarker Associated with Bone Tissue Alterations.
International journal of molecular sciences - 23 Jan 2024
Usategui-Martín Ricardo, Galindo-Cabello Nadia, Pastor-Idoate Salvador, Fernández-Gómez José María, Del Real Álvaro, Ferreño Diego, Lapresa Rebeca, Martín-Rodriguez Francisco, Riancho José A, Almeida Ángeles, Pérez-Castrillón José Luis
Abstract excerpt
Metabolic bone diseases cover a broad spectrum of disorders that share alterations in bone metabolism that lead to a defective skeleton, which is associated with increasing morbidity, disability, and mortality. There is a close connection between the etiology of metabolic bone diseases and genetic factors, with TP53 being one of the genes associated therewith. The single nucleotide polymorphism (SNP) Arg72Pro of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.