Article
Individually tailored screening of susceptibility to sarcopenia using p53 codon 72 polymorphism, phenotypes, and conventional risk factors.
Disease markers - 1 Jan 2014
Di Renzo Laura, Gratteri Santo, Sarlo Francesca, Cabibbo Andrea, Colica Carmen, De Lorenzo Antonino
Abstract excerpt
BACKGROUND AND AIM: p53 activity plays a role in muscle homeostasis and skeletal muscle differentiation; all pathways that lead to sarcopenia are related to p53 activities. We investigate the allelic frequency of the TP53 codon 72 in exon 4 polymorphism in the Italian female population and the association with appendicular skeletal muscle mass index in normal weight (NW), normal weight obese (NWO), and...
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