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Article

Case report of penile squamous cell carcinoma continuous treatment with BRCA2 mutation.

World journal of surgical oncology - 9 Feb 2024

Zhang Qing, Li Yaping, Zhang Yanrui, Deng Zhiping, Ding Yi

Abstract excerpt

BACKGROUND: Penile squamous cell carcinoma (PSCC) is a highly aggressive malignancy with a poor prognosis. BRCA1/2 mutations are associated with impaired DNA double-strand break repair and are among the common mutations in penile cancer, potentially paving the way for poly ADP-ribose polymerase inhibitor therapy. CASE PRESENTATION: We report a 65-year-old male with PSCC who progressed to thigh metastasis at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38336701
DOI: 10.1186/s12957-024-03305-9
PMCID: PMC10854037

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