Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New Insights into the Molecular Profile of Penile Squamous Cell Carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2021

McGregor Bradley A, Sonpavde Guru P

Abstract excerpt

Genomic alterations in penile squamous cell carcinoma (PSCC) appear similar to squamous cell carcinomas of the head and neck and esophagus but not lung, skin, bladder, and cervix. PSCCs display genomic heterogeneity, low mutation burden, and potentially actionable alterations in the Notch, DNA repair, kinase, and cell-cycle pathways.See related article by Chahoud et al., p. 2560.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Squamous Cell
Share to Genomics
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Penile Neoplasms

Source

Identifiers

PMID: 33653819
DOI: 10.1158/1078-0432.CCR-21-0139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New Insights into the Molecular Profile of Penile Squamous Cell Carcinoma.PMID 33653819Read ↗

Pathogenesis of Penile Squamous Cell Carcinoma: Molecular Update and Systematic Review.Semantic proximity Read ↗

Whole-exome Sequencing in Penile Squamous Cell Carcinoma Uncovers Novel Prognostic Categorization and Drug Targets Similar to Head and Neck Squamous Cell Carcinoma.Semantic proximity Read ↗

Molecular characterization and integrative genomic analysis of a panel of newly established penile cancer cell lines.Semantic proximity Read ↗

Molecular characterization of metastatic penile squamous cell carcinoma in developing countries and its impact on clinical outcomes: LACOG 2018 translational study.Semantic proximity Read ↗

The molecular pathogenesis of penile carcinoma—current developments and understandingSemantic proximity Read ↗

Mutational landscape of penile squamous cell carcinoma in a Chinese populationSemantic proximity Read ↗

Comprehensive Genomic Profiling of Advanced Penile Carcinoma Suggests a High Frequency of Clinically Relevant Genomic Alterations.Semantic proximity Read ↗

Comprehensive genomic profiling of penile squamous cell carcinoma and the impact of human papillomavirus status on immune-checkpoint inhibitor-related biomarkers.Semantic proximity Read ↗

Genomic Profiles and Clinical Outcomes of Penile Squamous Cell Carcinoma With Elevated Tumor Mutational BurdenSemantic proximity Read ↗

Understanding genomics and the immune environment of penile cancer to improve therapy.Semantic proximity Read ↗

Genomic Profiling of Human Penile Carcinoma Predicts Worse Prognosis and SurvivalSemantic proximity Read ↗

Genome-wide methylation and transcriptome analysis in penile carcinoma: uncovering new molecular markersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.