Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole-exome Sequencing in Penile Squamous Cell Carcinoma Uncovers Novel Prognostic Categorization and Drug Targets Similar to Head and Neck Squamous Cell Carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2021

Chahoud Jad, Gleber-Netto Frederico O, McCormick Barrett Z, Rao Priya, Lu Xin, Guo Ming, Morgan Maggaret B, Chu Randy A, Martinez-Ferrer Magaly, Eterovic Agda Karina, Pickering Curtis R, Pettaway Curtis A

Abstract excerpt

PURPOSE: Penile squamous cell carcinoma (PSCC) is rare with limited treatment options. We report the first whole-exome sequencing (WES) analysis and compare the molecular landscape of PSCC with other squamous cell carcinomas (SCC), with the goal to identify common novel targets. EXPERIMENTAL DESIGN: PSCC and matched normal penile tissues from 34 prospectively followed patients, underwent genomic WES and human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Management
Share to Disease Susceptibility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exome Sequencing

Share to Molecular Targeted Therapy

Share to Neoplasm Grading

Share to Neoplasm Staging

Share to Penile Neoplasms

Share to Squamous Cell Carcinoma of Head and Neck

Source

Identifiers

PMID: 33441293
DOI: 10.1158/1078-0432.CCR-20-4004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole-exome Sequencing in Penile Squamous Cell Carcinoma Uncovers Novel Prognostic Categorization and Drug Targets Similar to Head and Neck Squamous Cell Carcinoma.PMID 33441293Read ↗

New Insights into the Molecular Profile of Penile Squamous Cell Carcinoma.Semantic proximity Read ↗

Comprehensive genomic profiling of penile squamous cell carcinoma and the impact of human papillomavirus status on immune-checkpoint inhibitor-related biomarkers.Semantic proximity Read ↗

Pathogenesis of Penile Squamous Cell Carcinoma: Molecular Update and Systematic Review.Semantic proximity Read ↗

Genomic Profiles and Clinical Outcomes of Penile Squamous Cell Carcinoma With Elevated Tumor Mutational BurdenSemantic proximity Read ↗

Comprehensive Genomic Profiling of Advanced Penile Carcinoma Suggests a High Frequency of Clinically Relevant Genomic Alterations.Semantic proximity Read ↗

CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma.Semantic proximity Read ↗

Whole-exome sequencing identified mutational profiles of squamous cell carcinomas of anus.Semantic proximity Read ↗

Molecular characterization of metastatic penile squamous cell carcinoma in developing countries and its impact on clinical outcomes: LACOG 2018 translational study.Semantic proximity Read ↗

Molecular characterization and integrative genomic analysis of a panel of newly established penile cancer cell lines.Semantic proximity Read ↗

Mutational landscape of penile squamous cell carcinoma in a Chinese populationSemantic proximity Read ↗

Single-cell Atlas of Penile Cancer Reveals TP53 Mutations as a Driver of an Aggressive Phenotype, Irrespective of Human Papillomavirus Status, and Provides Clues for Treatment Personalization.Semantic proximity Read ↗

Characterizing the mutational landscape of sinonasal squamous cell carcinoma using whole-exome sequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.