Article
Risk factors and molecular characterization of penile cancer: impact on prognosis and potential targets for systemic therapy.
Current opinion in urology - 1 Mar 2020
Thomas Anita, Vanthoor Joren, Vos Gigi, Tsaur Igor, Albersen Maarten
Abstract excerpt
PURPOSE OF REVIEW: To provide a comprehensive summary of risk factors, molecular machinery as well as potential therapeutic targets with a particular focus on literature published in the last 2 years on prognosis and treatment of penile cancer (PeCa). RECENT FINDINGS: E2F, LAMC2, MAML2, ID1 and IGFBP2 proteins were demonstrated to play a critical role for aggressive tumor behavior and might predict poor survival...
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