Article
Sex-biased genetic regulation of inflammatory proteins in the Dutch population.
BMC genomics - 8 Feb 2024
Boahen Collins K, Abee Hannah, Ponce Isis Ricaño, Joosten Leo A B, Netea Mihai G, Kumar Vinod
Abstract excerpt
BACKGROUND: Significant differences in immune responses, prevalence or susceptibility of diseases and treatment responses have been described between males and females. Despite this, sex-differentiation analysis of the genetic architecture of inflammatory proteins is largely unexplored. We performed sex-stratified meta-analysis after protein quantitative trait loci (pQTL) mapping using inflammatory biomarkers...
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