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Article

Artesunate inhibits macrophage-like phenotype switching of vascular smooth muscle cells and attenuates vascular inflammatory injury in atherosclerosis via NLRP3.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Mar 2024

Liu Ping, Wang Yuqi, Tian Keke, Bai Xinyu, Wang Yaowen, Wang Yan

Abstract excerpt

Inflammation is one of the main pathogenic factors of atherosclerosis (AS), and the phenotypic transformation of macrophages in human vascular smooth muscle cells (HVSMCs) contributes to the inflammatory injury of blood vessels and the formation of atherosclerotic plaques. Artesunate reportedly exerts anti-inflammatory activity against AS. Herein, we aimed to explore the artesunate-mediated anti-inflammatory and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to NLR Family, Pyrin Domain-Containing 3 Protein

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Identifiers

PMID: 38325261
DOI: 10.1016/j.biopha.2024.116255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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