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Article

Cell fate regulation governed by p53: Friends or reversible foes in cancer therapy.

Cancer communications (London, England) - 1 Mar 2024

Song Bin, Yang Ping, Zhang Shuyu

Abstract excerpt

Cancer is a leading cause of death worldwide. Targeted therapies aimed at key oncogenic driver mutations in combination with chemotherapy and radiotherapy as well as immunotherapy have benefited cancer patients considerably. Tumor protein p53 (TP53), a crucial tumor suppressor gene encoding p53, regulates numerous downstream genes and cellular phenotypes in response to various stressors. The affected genes are...

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Identifiers

PMID: 38311377
DOI: 10.1002/cac2.12520
PMCID: PMC10958678

Genes

TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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