Article
Proinflammatory phenotype of B10 and B10pro cells elicited by TNF-α in rheumatoid arthritis.
Annals of the rheumatic diseases - 11 Apr 2024
Hu Fanlei, Shi Lianjie, Liu Xiaohang, Chen Yingjia, Zhang Xia, Jia Yuan, Liu Xu, Guo Jianping, Zhu Huaqun, Liu Hongjiang, Xu Liling, Li Yingni, Wang Ping, Fang Xiangyu, Xue Jimeng, Xie Yang, Wei Chaonan, Song Jing, Zheng Xi, Liu Yan-Ying, Li Yuhui, Ren Limin, Xu Dakang, Lu Liwei, Qiu Xiaoyan, Mu Rong, He Jing, Wang Min, Zhang Xuan, Liu Wanli, Li Zhanguo
Abstract excerpt
OBJECTIVES: B10 and B10pro cells suppress immune responses via secreting interleukin (IL)-10. However, their regulators and underlying mechanisms, especially in human autoimmune diseases, are elusive. This study aimed to address these questions in rheumatoid arthritis (RA), one of the most common highly disabling autoimmune diseases. METHODS: The frequencies and functions of B10 and B10pro cells in healthy...
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