Article
Functional Variants in MicroRNAs (rs895819, rs11614913 and rs2910164) Are Associated with Susceptibility and Clinicopathological Features in Mexican Patients with Colorectal Cancer.
Archives of Iranian medicine - 1 Aug 2023
Trujillo-Fernández Yuri Giovanna Vanessa, Yzabal-Barbedillo Carmen, Saucedo-Sarinaña Anilú Margarita, Tovar-Jácome César de Jesús, Godínez-Rodríguez Miriam Yadira, Barros-Núñez Patricio, Gallegos-Arreola Martha Patricia, Juárez-Vázquez Clara Ibet, Pineda-Razo Tomás Daniel, Marín-Contreras María Eugenia, Rosales-Reynoso Mónica Alejandra
Abstract excerpt
BACKGROUND: miRNAs are non-coding RNAs participating actively in the post-translational regulation of oncogenes, tumor suppressor, and DNA repair genes implicated in colorectal cancer (CRC). This study aims to examine the association of the variants miR-27a (rs895819 A>G), miR-196a2 (rs11614913 T>G) and miR-146a (rs2910164 C>G) in Mexican CRC patients. METHODS: DNA samples from 183 patients and 186 healthy...
Read the complete abstract on PubMed