MIR196A2 rs11614913 contributes to susceptibility to colorectal cancer in Iranian population: A multi-center case-control study and meta-analysis.

doi:10.1016/j.gene.2018.05.082

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MIR196A2 rs11614913 contributes to susceptibility to colorectal cancer in Iranian population: A multi-center case-control study and meta-analysis.

Gene - 30 Aug 2018

Haerian Monir Sadat, Haerian Batoul Sadat, Molanaei Saadat, Kosari Farid, Sabeti Shahram, Bidari-Zerehpoosh Farahnaz, Abdolali Ebrahim

Abstract excerpt

Maturation of MIR196A2 as a gene regulator with a high potential for targeted cancer therapy can be modulated by the rs11614913 polymorphism. Several studies evaluating the association between this variant and pathogenesis of colorectal cancer (CRC) found significant results in various ethnic groups. This study aimed at investigating this relationship in a large sample size of Iranians as well as in a systematic...

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PMID: 29802998
DOI: 10.1016/j.gene.2018.05.082

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