Article
Associations of single nucleotide polymorphisms in miR-146a, miR-196a, miR-149 and miR-499 with colorectal cancer susceptibility.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Du Wei, Ma Xue-Lei, Zhao Chong, Liu Tao, Du Yu-Liang, Kong Wei-Qi, Wei Ben-Ling, Yu Jia-Yun, Li Yan-Yan, Huang Jing-Wen, Li Zi-Kang, Liu Lei
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs) are an abundant class of endogenous small non-coding RNAs of 20-25 nucleotides in length that function as negative gene regulators. MiRNAs play roles in most biological processes, as well as diverse human diseases including cancer. Recently, many studies investigated the association between SNPs in miR-146a rs2910164, miR-196a2 rs11614913, miR-149 rs229283, miR-499 rs3746444 and...
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