Article
A functional polymorphism in miRNA-196a2 is associated with colorectal cancer risk in a Chinese population.
DNA and cell biology - 1 Mar 2012
Zhu Lingjun, Chu Haiyan, Gu Dongying, Ma Lan, Shi Danni, Zhong Dongyan, Tong Na, Zhang Zhengdong, Wang Meilin
Abstract excerpt
Single-nucleotide polymorphisms in microRNAs (miRNAs) may alter miRNA expression levels or processing and, thus, may contribute to cancer development. We hypothesized that miRNA-196a2 polymorphism is associated with risk of colorectal cancer (CRC). In a case-control study of 573 patients with CRC and 588 cancer-free controls frequency matched by age and sex, we genotyped the functional polymorphism rs11614913...
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