Article
Association between genetic variants in pre-miRNA and colorectal cancer risk in a Chinese population.
Journal of cancer research and clinical oncology - 1 Aug 2013
Lv Meili, Dong Wei, Li Lijuan, Zhang Lushun, Su Xiaowei, Wang Li, Gao Linbo, Zhang Lin
Abstract excerpt
INTRODUCTION: Single-nucleotide polymorphisms (SNPs) in pre-miRNAs may alter microRNA expression levels or processing and then contribute to the susceptibility of cancer development. We hypothesized that SNPs in pre-miRNAs may be associated with the risk of colorectal cancer (CRC). MATERIALS AND METHODS: We genotyped four common polymorphisms (i.e., rs11614913, rs3746444, rs2910164, and rs2292832) in pre-miRNAs...
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