Article
Patterns of lower risk myelodysplastic syndrome progression: factors predicting progression to high-risk myelodysplastic syndrome and acute myeloid leukemia.
Haematologica - 1 Jul 2024
Jain Akriti G, Ball Somedeb, Aguirre Luis, Al Ali Najla, Kaldas David, Tinsley-Vance Sara, Kuykendall Andrew, Chan Onyee, Sweet Kendra, Lancet Jeffrey E, Padron Eric, Sallman David A, Komrokji Rami
Abstract excerpt
The patterns of low-risk myelodysplastic syndrome (MDS) progression and the clinical and molecular features of those patterns have not been well described. We divided our low-risk (LR) MDS patients (N=1,914) into 4 cohorts: 1) patients who remained LR-MDS (LR-LR; N=1,300; 68%), 2) patients who progressed from LR to high-risk (HR) MDS (LR-HR) without transformation into acute myeloid leukemia (AML) (N=317; 16.5%),...
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