Article
Advances in the management of higher-risk myelodysplastic syndromes: future prospects.
Leukemia & lymphoma - 1 Sept 2024
Gener-Ricos Georgina, Rodriguez-Sevilla Juan Jose, Urrutia Samuel, Bataller Alex, Bazinet Alexandre, Garcia-Manero Guillermo
Abstract excerpt
Higher-risk myelodysplastic syndromes (HR-MDS) are defined using a number of prognostic scoring systems that include the degree of cytopenias, percentage of blasts, cytogenetic alterations, and more recently genomic data. HR-MDS encompasses characteristics such as progressive cytopenias, increased bone marrow blasts, unfavorable cytogenetics, and an adverse mutational profile. Survival is generally poor, and...
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