Article
Distinct mutation profile and prognostic relevance in patients with hypoplastic myelodysplastic syndromes (h-MDS).
Oncotarget - 27 Sept 2016
Yao Chi-Yuan, Hou Hsin-An, Lin Tzung-Yi, Lin Chien-Chin, Chou Wen-Chien, Tseng Mei-Hsuan, Chiang Ying-Chieh, Liu Ming-Chih, Liu Chia-Wen, Kuo Yuan-Yeh, Wu Shang-Ju, Liao Xiu-Wen, Lin Chien-Ting, Ko Bor-Shen, Chen Chien-Yuan, Hsu Szu-Chun, Li Chi-Cheng, Huang Shang-Yi, Yao Ming, Tang Jih-Luh, Tsay Woei, Liu Chieh-Yu, Tien Hwei-Fang
Abstract excerpt
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematologic malignancies. Although most MDS patients have normal or increased BM cellularity (NH-MDS), some have hypocellular BM (h-MDS). The reports concerning the differences in genetic alterations between h-MDS and NH-MDS patients are limited. In this study, 369 MDS patients diagnosed according to the WHO 2008 criteria were recruited. h-MDS patients...
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