Article
A novel approach to defining progression in MDS and precursor myeloid conditions in the MDS Natural History Study.
Blood advances - 28 Apr 2026
DeZern Amy E, Gillis Nancy, Otterstatter Michael, Abel Gregory, Padron Eric, Deeg H Joachim, Al Baghdadi Tareq, Liu Jane, Xie Zhuoer, Zhang Ling, Moscinski Lynn, Kroft Steven, Harrington Alexandra, Foran James, Komrokji Rami, Starczynowski Daniel, Gore Steven, Saber Wael, Bejar Rafael, Lindsley R C, Sherman Seth, Lee Cecilia, DiFronzo Nancy, Walter Matthew, Sekeres Mikkael A
Abstract excerpt
ABSTRACT: Patients at risk for progression from myeloid precursor states (idiopathic cytopenia of undetermined significance [ICUS] and clonal cytopenia of undetermined significance [CCUS]) to myelodysplastic syndrome (MDS) are not well defined. Epidemiologic risk factors, clonal changes for MDS development, and evolution from one MDS state to another were available in the MDS Natural History Study (NHS), a...
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