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Incorporation mutational profile might reduce the importance of blast count in prognostication of low-risk myelodysplastic syndromes.

British journal of haematology - 1 Nov 2024

García-Culebras Marta, Alcalde Patricia, Márquez-Malaver Francisco J, Carrillo Estrella, Soria Elena, Prats Concepción, Morales Rosario, Vargas María T, Pérez-Simón Jose Antonio, Falantes Jose F

Abstract excerpt

Addition of molecular data to prognostic models has improved risk stratification of myelodysplastic neoplasms (MDS). However, the role of molecular lesions, particularly in the group of low-risk disease (LR-MDS), is uncertain. We evaluated a set of 227 patients with LR-MDS. Overall survival (OS) and probability of leukaemic progression were the main endpoints. RUNX1 was associated with lower OS and SF3B1 with a...

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PMID: 39197431
DOI: 10.1111/bjh.19714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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