Article
Prognostic impact of SF3B1 mutation and multilineage dysplasia in myelodysplastic syndromes with ring sideroblasts: a Mayo Clinic study of 170 informative cases.
Haematologica - 1 Aug 2024
Farrukh Faiqa, Abdelmagid Maymona, Mangaonkar Abhishek, Patnaik Mrinal, Al-Kali Aref, Elliott Michelle A, Begna Kebede H, Hook Christopher C, Hogan William J, Pardanani Animesh, Litzow Mark R, Ketterling Rhett P, Gangat Naseema, Arber Daniel A, Orazi Attilio, He Rong, Reichard Kaaren, Tefferi Ayalew
Abstract excerpt
The revised 4th edition of the World Health Organization (WHO4R) classification lists myelodysplastic syndromes with ring sideroblasts (MDS-RS) as a separate entity with single lineage (MDS-RS-SLD) or multilineage (MDS-RS-MLD) dysplasia. The more recent International Consensus Classification (ICC) distinguishes between MDS with SF3B1 mutation (MDS-SF3B1) and MDS-RS without SF3B1 mutation; the latter is instead...
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