Differentiating Pathologic from Physiologic Fibrinolysis: Not as Simple as Conventional Thrombelastography.

doi:10.1097/XCS.0000000000001027

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Article

Differentiating Pathologic from Physiologic Fibrinolysis: Not as Simple as Conventional Thrombelastography.

Journal of the American College of Surgeons - 1 Jul 2024

Moore Hunter B, Barrett Christopher D, Moore Ernest E, Pieracci Fredric M, Sauaia Angela

Abstract excerpt

BACKGROUND: Conventional rapid thrombelastography (rTEG) cannot differentiate fibrinolysis shutdown from hypofibrinolysis, as both of these patient populations have low fibrinolytic activity. Tissue plasminogen activator (tPA) TEG can identify depletion of fibrinolytic inhibitors, and its use in combination with rTEG has the potential to differentiate all 3 pathologic fibrinolytic phenotypes after trauma. We...

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PMID: 38299576
DOI: 10.1097/XCS.0000000000001027

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