Article

Injury Severity is a Key Contributor to Coagulation Dysregulation and Fibrinogen Consumption

2024-01-20

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Traumatic injury is a leading cause of death for those under the age of 45, with 40% occurring due to hemorrhage. Severe tissue injury and hypoperfusion lead to marked changes in coagulation, thereby preventing formation of a stable blood clot and increasing hemorrhage associated mortality. <h4>Objectives</h4> We aimed to quantify changes in clot formation and mechanics occ...

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Literature Corpus work: d440390f-c8c3-55db-893b-563c3a27f600
DOI: 10.1101/2024.01.16.575945

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