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Article

Association of fibrinolysis phenotype with patient outcomes following traumatic brain injury.

The journal of trauma and acute care surgery - 1 Mar 2024

Durbin Samantha, Brito Alexandra, Johnson Alicia, Cotton Bryan, Rowell Susan, Schreiber Martin A

Abstract excerpt

BACKGROUND: Impaired coagulation is associated with elevated risk of mortality in trauma patients. Prior studies have demonstrated increased mortality in patients with hyperfibrinolysis (HF) and fibrinolysis shutdown (SD). In addition, prior studies have demonstrated no effect of tranexamic acid (TXA) on fibrinolysis phenotypes. We examined the association of admission fibrinolysis phenotype with traumatic brain...

Topics

Humans
Fibrinolysis
Brain Injuries, Traumatic
Blood Coagulation Disorders
Tranexamic Acid
Phenotype
Antifibrinolytic Agents

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37700441
DOI: 10.1097/TA.0000000000004122
PMCID: PMC10922039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Association of fibrinolysis phenotype with patient outcomes following traumatic brain injury.PMID 37700441Read ↗

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