Genetic polymorphism of WNT9A is functionally associated with thumb osteoarthritis in the Chinese population.

doi:10.1186/s42358-023-00337-9

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Article

Genetic polymorphism of WNT9A is functionally associated with thumb osteoarthritis in the Chinese population.

Advances in rheumatology (London, England) - 29 Jan 2024

Dai Jian, Jiang Haitao, Cheng Zhang, Li Yao, Yang Zhaoqi, Cheng Chuan, Tang Xiaoming

Abstract excerpt

BACKGROUND: In a recent genome-wide association study, novel genetic variations of WNT9A were reported to be involved in the etiopathogenesis of thumb osteoarthritis (TOA) in Caucasians. Our purposes were to replicate the association of WNT9A with the development of TOA in the Chinese population and to further unveil the functional role of the risk variants. METHODS: SNP rs11588850 of WNT9A were genotyped in 953...

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PMID: 38287451
DOI: 10.1186/s42358-023-00337-9
PMCID: PMC13488746

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WNT9A

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