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Familial Clustering and Genetic Analysis of Severe Thumb Carpometacarpal Joint Osteoarthritis in a Large Statewide Cohort

2022-03-08

Abstract excerpt

<h4>Objectives</h4> The objectives of this study are to 1) identify individuals that required surgery for thumb carpometacarpal osteoarthritis (CMCJ OA), 2) determine if CMCJ OA clusters in multigenerational families, 3) define the magnitude of familial risk of CMCJ OA, 4) identify risk factors associated with CMCJ OA and 5) identify rare genetic variants that segregate with familial CMCJ OA. <h4>Methods</h4> We...

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Literature Corpus work
82920bb2-df81-568c-9c3c-266ab4254ef3
DOI
10.1101/2022.03.03.22271851
Open publication

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Familial Clustering and Genetic Analysis of Severe Thumb Carpometacarpal Joint Osteoarthritis in a Large Statewide CohortDOI 10.1101/2022.03.03.22271851
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