Article
Genetic polymorphisms of SPP1 and MGP are associated with thumb osteoarthritis: a replication study in the Chinese population.
Molecular biology reports - 18 Mar 2026
Dai Jian, Jiang Haitao, Ma Jian, Zhu Hai, Li Yao, Tang Xiaoming
Abstract excerpt
BACKGROUND: In a recent meta-analysis of genome-wide association studies, three novel common variants were reported to be associated with erosive hand osteoarthritis. In this study, we aimed to investigate whether rs17013495, rs11243284 and rs1800801 are associated with the development of thumb OA in the Chinese population. METHODS: All three were genotyped in 529 patients and 822 healthy controls. The gene...
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