Article
Exploring the role of the WNT5A rs566926 polymorphism and its interactions in non-syndromic orofacial cleft: a multicenter study in Brazil.
Journal of applied oral science : revista FOB - 1 Jan 2024
Lara Lorraynne Dos Santos, Coletta Ricardo D, Assis Machado Renato, Querino Rocha de Oliveira Lilianny, Martelli Júnior Hercílio, de Almeida Reis Silvia Regina, Scariot Rafaela, Evaristo Ricci Volpato Luiz
Abstract excerpt
BACKGROUND: Associations between the WNT5A rs566926 variant and non-syndromic orofacial cleft (NSOC) have been reported in different populations. OBJECTIVE: This study aimed to investigate the role of the rs566926 single nucleotide polymorphism (SNP) in WNT5A and its interactions with SNPs in BMP4, FGFR1, GREM1, MMP2, and WNT3 in the occurrence of NSOC in a Brazilian population. METHODOLOGY: A case-control...
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