Article
Association of common variants in the calcium-sensing receptor gene with serum calcium levels in East Asians.
Journal of human genetics - 1 Aug 2015
Vinayagamoorthy Nadimuthu, Yim Seon-Hee, Jung Seung-Hyun, Park Sung-Won, Kim Young Jin, Kim Bong-Jo, Chung Yeun-Jun
Abstract excerpt
Calcium is a universal intracellular messenger that has an important role in controlling various cellular processes. In this study, we explored genetic polymorphisms to identify novel loci influencing serum calcium levels in East Asians through a two-stage genome-wide association study with the sample of 8642 unrelated Koreans (4558 for discovery and 4093 for replication). Using single-nucleotide polymorphism...
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