Article

Sex-specific phenotypic effects and evolutionary history of an ancient polymorphic deletion of the human growth hormone receptor

2019-10-01

Abstract excerpt

<h4>ABSTRACT</h4> The deletion of the third exon of the growth hormone receptor ( GHR ) is one of the most common genomic structural variants in the human genome. This deletion ( GHRd3) has been linked to response to growth hormone, placenta size, birth weight, growth after birth, time of puberty, adult height, and longevity. However, its evolutionary history and the molecular mechanisms through which it affect...

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Literature Corpus work: 206fff06-733c-5459-bf9e-76ec7e9bff51
DOI: 10.1101/788653

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