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Article

Pharmacogenetic markers to predict the clinical response to methotrexate in south Indian Tamil patients with psoriasis.

European journal of clinical pharmacology - 1 Aug 2017

Indhumathi S, Rajappa Medha, Chandrashekar Laxmisha, Ananthanarayanan P H, Thappa D M, Negi V S

Abstract excerpt

INTRODUCTION: Despite the advent of several new systemic therapies, methotrexate remains the gold standard for the treatment of moderate to severe psoriasis. However, there exists a significant heterogeneity in individual response to methotrexate. There are no consistently reliable markers to predict methotrexate treatment response till date. OBJECTIVES: We aimed to demonstrate the association of certain genetic...

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PMID: 28444425
DOI: 10.1007/s00228-017-2255-x

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FOXP3

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