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Genetics of Psoriasis and Pharmacogenetics of Biological Drugs

1 Jan 2013

Abstract excerpt

Psoriasis is a chronic inflammatory disease of the skin. The causes of psoriasis are unknown, although family and twin studies have shown genetic factors to play a key role in its development. The many genes associated with psoriasis and the immune response include TNF α , IL23, and IL12. Advances in knowledge of the pathogenesis of psoriasis have enabled the development of new drugs that target cytokines (e.g.,...

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PMID: 24069534
DOI: 10.1155/2013/613086

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