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Ribosomal frameshifting at normal codon repeats recodes functional chimeric proteins in human

10 Jan 2024

Abstract excerpt

Ribosomal frameshifting refers to the process that ribosomes slip into +1 or -1 reading frame, thus produce chimeric trans-frame proteins. In viruses and bacteria, programmed ribosomal frameshifting can produce essential trans-frame proteins for viral replication or regulation of other biological processes. In humans, however, functional trans-frame protein derived from ribosomal frameshifting is scarcely...

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PMID: 38281188
DOI: 10.1093/nar/gkae035

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