Article
HLA-DPB1 genotype variants predict DP molecule cell surface expression and DP donor specific antibody binding capacity.
Frontiers in immunology - 1 Jan 2023
Yin Yuxin, Soe Nwe Nwe, Valenzuela Nicole M, Reed Elaine F, Zhang Qiuheng
Abstract excerpt
The contribution of alloresponses to mismatched HLA-DP in solid organ transplantation and hematopoietic stem cell transplantation (HCT) has been well documented. Exploring the regulatory mechanisms of DPB1 alleles has become an important question to be answered. In this study, our initial investigation focused on examining the correlation between the rs9277534G/A SNP and DPB1 mRNA expression. The result showed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
