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Article

Analysis of HIF-1α expression and genetic polymorphisms in human clear cell renal cell carcinoma.

Pathology oncology research : POR - 1 Jan 2023

Vargova Daniela, Kolková Zuzana, Dargaj Jan, Bris Lukas, Luptak Jan, Dankova Zuzana, Franova Sona, Svihra Jan, Slávik Pavol, Sutovska Martina

Abstract excerpt

Introduction: Clear cell renal cell carcinoma (ccRCC) is mostly diagnosed incidentally and has relatively high recurrence rates. Alterations in VHL/HIF and mTOR pathways are commonly present in ccRCC. The present study attempted to identify potential diagnostic markers at the biochemical and molecular level. Methods: In total, 54 subjects (36 patients with ccRCC and 18 cancer-free controls) were enrolled. ELISA...

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Share to Carcinoma, Renal Cell
Share to Hypoxia-Inducible Factor 1, alpha Subunit

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to TOR Serine-Threonine Kinases

Source

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Identifiers

PMID: 38273861
DOI: 10.3389/pore.2023.1611444
PMCID: PMC10808674

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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