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Article

[Somatic mutations of VHL gene and HIF-1alpha expression in primary renal clear cell carcinomas].

Zhonghua wai ke za zhi [Chinese journal of surgery] - 22 Feb 2004

Guo Hong-feng, Gong Kan, Zou Shuang-mei, Zhang Zhi-wen, Liu Xiu-yun, Na Xi, Wu Guan, Na Yan-qun

Abstract excerpt

OBJECTIVE: To evaluate the significance of somatic mutations of VHL gene and hypoxia-inducible factor-1alpha (HIF-1alpha) expression in primary renal clear cell carcinoma (RCC). METHODS: Mutation of VHL gene and HIF-1alpha expression were detected by means of PCR, denaturing high-performance liqu...

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Topics

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Share to Adenocarcinoma, Clear Cell
Share to Carcinoma, Renal Cell
Share to Chromatography, Liquid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypoxia-Inducible Factor 1, alpha Subunit

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Share to Kidney Neoplasms

Share to Ubiquitin-Protein Ligases

Share to Von Hippel-Lindau Tumor Suppressor Protein

Source

Identifiers

PMID: 15062033

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15062033-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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[Somatic mutations of VHL gene and HIF-1alpha expression in primary renal clear cell carcinomas].PMID 15062033Read ↗

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